Which statement accurately describes a difference in bradykinin effects between ACE inhibitors and ARBs?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Rasmussen Pharmacology Exam 3. This quiz includes multiple-choice questions with hints and explanations. Review essential pharmacological concepts and get ready for your exam!

Multiple Choice

Which statement accurately describes a difference in bradykinin effects between ACE inhibitors and ARBs?

Explanation:
Bradykinin is normally inactivated by angiotensin-converting enzyme. When you use an ACE inhibitor, you block this enzyme, which not only reduces angiotensin II formation but also prevents bradykinin breakdown. The result is higher bradykinin levels, which helps explain why ACE inhibitors can cause a dry cough and, rarely, angioedema. ARBs, on the other hand, block the angiotensin II receptor without inhibiting ACE, so bradykinin degradation continues and its levels don’t rise. That difference is why the statement that bradykinin effects increase with ACE inhibitors but not with ARBs is correct.

Bradykinin is normally inactivated by angiotensin-converting enzyme. When you use an ACE inhibitor, you block this enzyme, which not only reduces angiotensin II formation but also prevents bradykinin breakdown. The result is higher bradykinin levels, which helps explain why ACE inhibitors can cause a dry cough and, rarely, angioedema. ARBs, on the other hand, block the angiotensin II receptor without inhibiting ACE, so bradykinin degradation continues and its levels don’t rise. That difference is why the statement that bradykinin effects increase with ACE inhibitors but not with ARBs is correct.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy